PT4 Unresponsive and very slow

[expost]

Long time PT4 user. v4.18.4 currently

I've been getting this error message for months. Housekeeping has not helped. It's gotten to the point where PT4 is crashing my (powerful) PC while I'm playing. HUD works only sometimes. Mucked cards feature takes at least 10 seconds to show up. I have tried a clean reinstall without success. Please help!