With PokerTracker4 closed open this file using TextEdit:
~/library/Application Support/PokerTracker 4/Config/GuiSettings.cfgScroll to the end and you should see:
[General]
RequestedPermissions=YChange "=Y" to "=N" and save your changes. This will tell PokerTracker 4 to re-request all of its permissions.
If not try removing PokerTracker 4 from all of the Privacy & Security permissions it has. Make sure to remove the permission by selecting PokerTracker 4 and clicking the minus button (do not just disable it). There are 5 sections within Privacy & Security where you should see it:
Accessibility
Files & Folders
Screen Recording
Automation (as far as I know isn't possible to remove the permission here, so don't worry about that if you can't)
App Management (this is only required if you play at PokerStars and have the Zoom Hud enabled, so you may not see it)
Run PokerTracker 4 again. It should now ask you to allow the permissions. Click OK to allow access to the Documents and Download folders. For the ones that offer to open system settings click that and enable the permission. When you enable the first permission it will show you two messages - one is PokerTracker 4 asking for the next permission and the other is the privacy settings asking to quit & reopen PokerTracker 4. Click Quit & Reopen first, and then enable the other permission(s). That should allow PokerTracker 4 to start up. If not reboot then press/hold the "Alt/Option" key while starting PokerTracker 4 to enable logging and then attach this file to a
Support Ticket:
\Users\{Mac Login}\Library\Application Support\PokerTracker 4\Logs\PokerTracker4.log